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03 January 2025

Prominent Efficacy and Good Safety of Sequential CD19 and CD22 CAR-T Therapy in Relapsed/Refractory Adult B-cell Acute Lymphoblastic Leukemia

Exp Hematol Oncol 2025: Phase 2 study showing sequential CD19/CD22 CAR-T therapy delivers high complete remission rates with manageable toxicity in adult r/r B-ALL, with most responders achieving MRD-negative status.

06 June 2025

Phase I trial validating a simplified autologous CD7 CAR-T manufacturing process without T-cell pre-selection, expanding accessibility for pediatric r/r T-ALL patients

Phase I trial validating a simplified autologous CD7 CAR-T manufacturing process without T-cell pre-selection, expanding accessibility for pediatric r/r T-ALL patients

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01 October 2024

BCMA/GPRC5D bispecific CAR T-cell therapy for relapsed/refractory multiple myeloma with extramedullary disease: a single-center, single-arm, phase 1 trial

BCMA/GPRC5D bispecific CAR T-cell therapy for relapsed/refractory multiple myeloma with extramedullary disease: a single-center, single-arm, phase 1 trial

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24 September 2025

Sequential CD19 and CD22 Chimeric Antigen Receptor T-cell Therapy for Childhood Refractory or Relapsed B-cell Acute Lymphocytic Leukaemia

Sequential CD19 and CD22 Chimeric Antigen Receptor T-cell Therapy for Childhood Refractory or Relapsed B-cell Acute Lymphocytic Leukaemia

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01 January 2026

Sequential CD7 CAR T-Cell Therapy and Allogeneic HSCT without GVHD Prophylaxis

N Engl J Med 2024: Landmark N Engl J Med study showing that CD7 CAR-T bridging to allogeneic HSCT without GVHD prophylaxis is feasible and effective for T-ALL patients, opening a new curative pathway.

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25 April 2023

Allogenic and Autologous Anti-CD7 CAR-T-cell Therapies in Relapsed or Refractory T-cell Malignancies

Allogenic and Autologous Anti-CD7 CAR-T-cell Therapies in Relapsed or Refractory T-cell Malignancies.

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