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a2ce77f8-f80e-404e-98e3-815845849111
01 October 2024

BCMA/GPRC5D bispecific CAR T-cell therapy for relapsed/refractory multiple myeloma with extramedullary disease: a single-center, single-arm, phase 1 trial

BCMA/GPRC5D bispecific CAR T-cell therapy for relapsed/refractory multiple myeloma with extramedullary disease: a single-center, single-arm, phase 1 trial
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  • 58505907-60ae-4c70-867a-e94e0847458e
    06 June 2025

    Phase I trial validating a simplified autologous CD7 CAR-T manufacturing process without T-cell pre-selection, expanding accessibility for pediatric r/r T-ALL patients

    Phase I trial validating a simplified autologous CD7 CAR-T manufacturing process without T-cell pre-selection, expanding accessibility for pediatric r/r T-ALL patients
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  • e4117934-1c21-4635-889e-eba61ba63563
    03 January 2025

    Prominent Efficacy and Good Safety of Sequential CD19 and CD22 CAR-T Therapy in Relapsed/Refractory Adult B-cell Acute Lymphoblastic Leukemia

    Exp Hematol Oncol 2025: Phase 2 study showing sequential CD19/CD22 CAR-T therapy delivers high complete remission rates with manageable toxicity in adult r/r B-ALL, with most responders achieving MRD-negative status.
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  • 640
    24 September 2025

    Sequential CD19 and CD22 Chimeric Antigen Receptor T-cell Therapy for Childhood Refractory or Relapsed B-cell Acute Lymphocytic Leukaemia

    Sequential CD19 and CD22 Chimeric Antigen Receptor T-cell Therapy for Childhood Refractory or Relapsed B-cell Acute Lymphocytic Leukaemia
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  • 85113981-02f6-4e76-9872-badfc62105ac
    01 January 2026

    Sequential CD7 CAR T-Cell Therapy and Allogeneic HSCT without GVHD Prophylaxis

    N Engl J Med 2024: Landmark N Engl J Med study showing that CD7 CAR-T bridging to allogeneic HSCT without GVHD prophylaxis is feasible and effective for T-ALL patients, opening a new curative pathway.
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  • 971d16d5-a0d6-4431-aa9c-a64dda2c6b49
    25 April 2023

    Allogenic and Autologous Anti-CD7 CAR-T-cell Therapies in Relapsed or Refractory T-cell Malignancies

    Allogenic and Autologous Anti-CD7 CAR-T-cell Therapies in Relapsed or Refractory T-cell Malignancies.
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